Restylane Refyne and Defyne Filler

Publish date: 2024-05-15

There's a new filler in town (actually, two new fillers) and they're billed as the next big thing in the fight against laugh lines. Galderma, the pharmaceutical company behind injectables like Restylane, Sculptra, and Dysport, has just announced FDA approval of two new fillers: Restylane Refyne and Defyne. The first was approved to treat moderate wrinkles and folds from the nose to mouth, while the latter is meant to plump and fill deep-set lines. Both are expected to be in doctors' offices around the country by early next year.

Aqua, Azure, Electric blue, Turquoise, Teal, Office supplies, Stationery, Box, Pen, Office instrument, pinterest

Courtesy of Galderma

While there are other fillers on the market that can plump wrinkles, Refyne and Defyne are meant to give a more natural-looking result than previously thought possible. Galderma claims results can last up to 12 months, which means you'll likely need to get pricked twice a year to keep things looking smooth. But it's the new type of hyaluronic acid in the filler gel that's the real news here. The new technology is called XpresHAn—which is pronounced like a French person trying to say the word expression—and it allows the hyaluronic acid gel to flex within the skin as you move your face. So whether you're smiling, frowning, or wrinkling your face any which way, the result looks soft and natural, not puffy or stiff.

Though new to the United States, both Restylane Refyne and Defyne have been used in Europe under the name Emervel since 2010.

Headshot of Jenna Rosenstein

Jenna Rosenstein is the Beauty Director at Harper's BAZAAR across both print and digital. While attending NYU, she held internships at Women’s Wear Daily, Bloomingdale’s, Harper’s BAZAAR, and Allure, the latter of which she parlayed into her first job as the Beauty Assistant. She left Allure three years later as the Senior Beauty Editor. She spent a few months at Refinery29 overseeing branded content in the same title, before finally landing back at BAZAAR to manage all beauty content. When she's not testing every lipstick known to mankind, getting zapped by new lasers, or interviewing experts and celebrities, you can find Rosenstein at home in New Jersey with her son, husband, and black cat named Maddie.

ncG1vNJzZmivp6x7qa3RqZyrq5KWx6Kt0WeaqKVfl7KiwdOyZqyjmaN6pK3RnmaaaWlog3d70Z6qrbGclrumedGenbKmlWKur7CMnZyfsZ6afA%3D%3D